Histosonda®

Bio Molecular Market size is World wide small due to the low development that ISH (In Situ Hybridization) technologies had in the past 40 years.

There are few companies in the world that commercialises probes for ISH, and most of them are Oligo probes of 20-40 pair of basis. Those companies have not developed new probes since long time ago.

Those Oligo Probes are small, unspecific and have complicated protocols, they need long incubation periods, and they must be storage and transport at cold temperatures.

There are very little choice among this different ISH probes, and the results obtained by those probes are very disappointing, they have lots of background, the results are some times hard to interpret and because the protocol is long and tedious, pathologists and technicians are never sure about the results obtained.

Those are the main reasons why some Pathologists and technicians still are using antibodies despite unespecificity, and hard background.

HistoSonda® is a technology that allows CENBIMO to produce probes longer than oligos, from 200 to 1800 pair of basis.

HistoSonda® highly Increases Specificity and Homology, and its protocol is as simple as immunohistochemistry procedure. It has only 60 minutes incubation and the results are fantastic with no background and allowing the pathologist to obtain more information from the tissue images.

The number of HistoSonda® Probes up to day is 27 and is continuously increasing, developing 2 new probes every trimester.

CENBIMO S.L has concentrated its efforts on developing probes that will solve some of the most common problems founded with antibodies and developing also probes that were not developed before and have a great scientific and clinical interest.

HistoSonda® will help pathologists to simplified diagnostic procedures by obtaining Yes or No results, this protocol only takes 3 hours maximum from dewaxing to counterstaining.

The long list of proves that already are available in the market, and the new demands from modern medicine much more implicated on gene expression and gene targeting, makes ISH as a lovable technology to be used much more frequently in pathology labs.

Bio Molecular technology is more needed and demanded due to a new generation of pharmaceutical drugs and treatments, those new drugs are more specific against concrete genes implicated on tumoral or viral process. Pathologists more often need a simply Yes or NO diagnostic tool like Histosonda®, with the guarantee of almost 100 % specificity.

The present and the future of Bio Molecular IVD technology is here and its name is HistoSonda®